Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial
St. Jude Children's Research Hospital
Summary
The purpose of the study is to determine if an adapted mobile cognitive behavioral therapy (CBT) app (WebMAP Onc) is more effective than standard pain education in reducing chronic pain and improving daily functioning in adolescent survivors of pediatric cancer. This randomized study led by St. Jude Children's Research Hospital will involve 228 participants (114 adolescent survivors and 114 caregivers) across four U.S. hospitals. Outcomes include pain reduction, improved function, and the role of social determinants of health. Assessments occur at baseline, post-treatment, and 3-month follow-up.
Description
Survivors of childhood cancer with lasting pain may have problems with daily life, such as paying attention, sleeping, or daily activities. A mobile cognitive behavioral therapy program (App) and patient education materials may be helpful for survivors with pain. Researchers at St. Jude Children's Research Hospital want to see if these tools can used to improve pain in survivors. Participants will be recruited from 4 sites: St. Jude Children's Research Hospital (SJCRH), Children's Healthcare of Atlanta (CHOA), Texas Children's Hospital (TCH), and Seattle Children's Hospital (SCH). Standard tr…
Eligibility
- Age range
- 10–17 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Adolescent Participants * 10-17-year-old survivors of childhood cancer or those who received cancer directed therapies (e.g., Langerhan's Histiocytosis) * At least one-year post treatment completion * Pain present for 3 months or longer * Pain interfering with at least one area of daily functioning * Parent/Caregiver Participants * ≥ 18 years of age * Legally authorized to provide informed consent for the adolescent participant Exclusion Criteria: * Adolescent Participants * Serious comorbid psychiatric condition * Current substance abuse as determin…
Interventions
- BehavioralCognitive Behavioral Therapy (CBT)
Receive mobile CBT
- BehavioralEducation
Receive educational materials
- OtherQuestionnaires
Ancillary studies
Location
- St. Jude Children's Research HospitalMemphis, Tennessee