A Medical Nutrition Supplement for Cystic Fibrosis
Ohio State University
Summary
The goal of this study is to learn if one nutrition supplement formula works better than a different formula in adults with cystic fibrosis. The main question being addressed is: Will certain atypical versions of certain nutrients outperform typical versions of these nutrients? This will be determined by examining blood measures of nutrient levels and/or indications of nutrient function indicators pre- and post-intervention. Participants will take the supplements for 6 weeks with a blood draw before and after that time.
Description
Background. For people with cystic fibrosis (CF), new drugs have extended life expectancy and improved quality of life. Yet, even with these improvements, people with CF still face shorter than normal life spans and constant threats of quality of life disruptions. One approach to attacking these hardships consists of treating nutritional deficiencies. However, that's not as simple as just giving standard nutrients. People with CF have trouble transporting certain nutrients from the digestive system. In theory, giving nutrients in certain forms might get past the CF associated difficulties. How…
Eligibility
- Age range
- 18–50 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Diagnosed with cystic fibrosis * Diagnosed with exocrine pancreatic insufficiency * 18 years old or older * Currently on modulator * Normal liver enzyme labs Exclusion Criteria: : * Non-English-speaking participants * Acute health crisis * Persistent elevation of liver enzymes \>6 months (E2) (ALT \>80 U/L) * History of liver abnormalities * If patients are currently taking Category A or Category B in the LiverTox categorization system * Recent vitamin D supplementation of 30 mcg/day or higher, vitamin E supplements of 200 IU/day or higher, or copper at 2 mg/day or hig…
Interventions
- Dietary SupplementCommon form supplementation
The intervention product would represent part of a typical supplement given to people including those with CF
- Dietary SupplementUncommon nutrient supplementation
The intervention product would represent part of a possible new supplement given to people including those with CF
Location
- Nationwide Children's Hospital-Ohio State UniversityColumbus, Ohio