Resilience Enhancement Utilizing an Electronic Frailty Index-Directed Care Pathway for Older Adults Receiving Chemotherapy (RESILIENCE-e): A Prospective Single-Arm Interventional Study
Wake Forest University Health Sciences
Summary
The study purpose is to gain a better understanding of the needs of adults aged 65 and older while they are receiving chemotherapy by measuring their resilience and tailor care plans based on their individual needs.
Description
This is a prospective single-arm intervention trial of patients aged 65 or older with an active cancer diagnosis who are planned to receive chemotherapy and are eFI (Electronic Health Record (EHR)-based frailty index) pre-frail or frail. Patients will be enrolled before initiation of chemotherapy. Following a baseline assessment, subjects will be provided with results regarding their frailty, will be offered referrals for supportive care interventions and will participate in weekly symptom reporting (electronic survey + phone call from research nurse) for 12 weeks. Follow-up assessments will…
Eligibility
- Age range
- 65+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: Patients with cancer: * Ability to understand and willingness to sign an IRB-approved informed consent * Age ≥ 65 years at the time of enrollment. * Planned to initiate an outpatient chemotherapy regimen for cancer treatment (any type or stage), either as an initial therapy or as a new line of therapy, with curative or palliative intent. * eFI pre-frail or frail status (available in EHR) within 30 days before enrollment. * Ability to read and understand the English language Providers: * Treating medical oncologist of at least one patient participant who enrolled on to t…
Interventions
- OtherSupportive Care
Geriatric assessment (GA) -guided supportive care and weekly Patient Reported Outcomes (PRO) symptom assessment
Locations (2)
- Levine Cancer InstituteCharlotte, North Carolina
- Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, North Carolina