Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy
Hartford HealthCare
Summary
The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss. Examples of pelvic floor symptoms include urinary incontinence, urinary urgency, urinary frequency, fecal incontinence, and vaginal prolapse. Participants in this study do not need to have any pelvic floor symptoms to enroll in the study. Understanding how different types of weight loss treatment impact pelvic floor symptoms will help clinicians guide which weight loss treatments are recommended for patients with pelvic floor symptoms in the future.
Description
Lower Urinary Tract Symptoms (LUTS) are defined as bothersome symptoms related to the storage of urine, voiding, and postvoid symptoms, and includes urgency, frequency, and urinary incontinence (UI). UI is the involuntary loss of urine and is a common and bothersome form of LUTS. The prevalence of urinary incontinence is high and increasing, with 61.8% of all women over 20 years old reporting urinary incontinence. High body mass index (BMI) is associated with higher risk of UI. In women with UI, modest weight loss due to behavioral changes or dieting has been shown to decrease the frequency of…
Eligibility
- Age range
- 18–90 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * female * 18-89 years old * any race/ethnicity * BMI ≥30 kg/m2 * current medical weight loss or surgical weight loss patient of Obesity Medicine and Metabolic \& Bariatric Surgery * able/willing to give informed consent * have a home scale to measure weight Patients meeting all the following criteria will be eligible to participate in the medical weight loss therapy arm: * prescribed and start a glucagon-like peptide-1 receptor agonist (GLP-1 RA) or a GLP-1/gastric inhibitory peptide (GIP1) * taking other weight loss agents (such as metformin) Patients meeting all the…
Interventions
- ProcedureBariatric Surgery
Patients in this arm plan to undergo gastric sleeve or gastric bypass surgery.
- DrugGLP1 receptor agonist
Patients in this arm plan to start a GLP-1 receptor agonist.
Location
- Hartford HospitalHartford, Connecticut