Myocardial Perfusion in Spontaneous Coronary Artery Dissection Using Stress Contrast Echocardiography
Mayo Clinic
Summary
This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Adult \>18 years old * Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history Exclusion Criteria: * Unable to give consent * Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine. * Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®. * Pregnant. * Unable to interrupt breastfeeding. * Within 3 months of a heart attack. * Severe aortic stenosis. * Severe, uncontrolled hypertension (\>200/110 m…
Interventions
- ProcedureStress Echocardiography with Contrast
Stress Echocardiography with Contrast will be used to assess heart function and blood flow response to stressors.
Location
- Mayo ClinicRochester, Minnesota