Children's Hospital Medical Center, Cincinnati
To develop and validate a urine drug screen to detect thebaine.
Inclusion Criteria: * Male or female * Ages 18-65 * Healthy Exclusion Criteria: * Allergy to poppy seeds, or any of the related food stuffs used in the study * Celiac disease or gluten sensitivity * Ongoing or opioid use in the past 6 months * History of renal or hepatic disease or dysfunction * Inability or unwillingness to give repeated urine specimens * Unwillingness to refrain from eating poppy seed-containing products during the two-day course of the study * Non-English speakers (due to study materials being in English) * BMI greater than 30 * Antibiotic use in the previous 2 months *…