Effects of Transcranial Ultrasound Stimulation (TUS) on Neurological and Cognitive Outcomes in Neurodegenerative Diseases.
Sanmai Technologies PBC dba Sanmai
Summary
The purpose of this study is to evaluate the safety and efficacy of transcranial focused ultrasound neuromodulation in improving neural function, cognitive and behavioral performance, and quality of life for patients with neurodegenerative diseases.
Eligibility
- Age range
- 18–80 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: Age 18-80 years Ability to read and understand English Clinical diagnosis of Alzheimer's, Parkinson's, Parkinson's dementia, mild cognitive impairment Normal or corrected to normal vision and hearing Must be medically stable as determined by investigators Exclusion Criteria: History of significant neurological disorders unrelated to the target disease Implanted medical devices or metal implants incompatible with TUS or MRI Uncontrolled heart or cardiac conditions or implants: severe arrhythmia, myocardial infarction, arterial angina Psychiatric Conditions: individ…
Interventions
- DeviceTranscranial focused ultrasound modulation administered to a region involved in disease pathology.
Using Sanmai's device to administer tFUS to regions of interest.
Location
- The Regenesis ProjectSanta Monica, California