Evaluation of Grape Consumption to Improve Muscle Strength and Cognitive Function
Western New England University
Summary
The goal of this clinical trial is to learn if eating grapes can improve muscle strength and thinking in generally healthy women over 65. The main questions it aims to answer are: Does eating grapes improve muscle strength in women over 65? Does eating grapes improve cognition in women over 65? Participants will be asked to take part in 4 sessions on campus. Each session will include: Functional muscle strength testing Cognitive testing Blood draws
Description
The goal of this project is to perform a translational study to evaluate the potential of grape consumption to improve muscle and cognitive function with female human volunteers. The study will examine the impact of grape consumption on the functional strength and cognition of females over the age of 65. We will recruit 35 women who are in good overall health. On Day 1, consented participants will undergo baseline screening and assessments and will receive education on dietary restrictions for the following two weeks. After the two-week run-in diet period, on Day 14 participants will complete…
Eligibility
- Age range
- 65+ years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * Healthy female (confirmed by medical history) * Aged 65 or older; * Able to walk household distances without assistance from another person * Non-smoker; * Dominant hand grip strength at or below normal value for age and gender; * Had not consumed recreational drugs for one week prior; * Agreed not to participate in any clinical or patch test studies at Day 1 through study completion; * Completed a medical intake; * Read, understood, and signed an informed consent. Exclusion Criteria: * Using nasally inhaled/systemic/topical corticosteroids within 4 weeks prior to and/…
Interventions
- Dietary SupplementGrape Powder
All participants will consume two 36g packets of grape powder (mixed with water) daily for two, 2-week periods during the study. Participants will mix pre-measured grape powder with water and drink twice a day (once in the morning and in the afternoon/evening) for two weeks.
Location
- Western New England UniversitySpringfield, Massachusetts