Menopausal Hormone Therapy And Neural Control Of Left Ventricular Function
Mayo Clinic
Summary
The purpose of this study is to compare left ventricular stroke volume and heart rate responses to bursts of SNA between PMF using, and not using, MHT.
Eligibility
- Age range
- 45–60 years
- Sex
- Female
- Healthy volunteers
- Not specified
Inclusion Criteria • \>45-60\< years of age Exclusion Criteria * Male sex * Females between STRAW+10 stages -5 and 0 * PMF in STRAW+10 stage +2 * PMF using oral hormone therapy * Females who entered menopause due to a surgical procedure or in response to pharmacotherapy (e.g., gonadotrophin releasing hormone agonists or chemotherapy) * Heart disease such as hypertropic cardiomyopathy, congenital abnormalities, chronic heart failure, valve disease, and a history of myocardial infarction * Medications that impact the central nervous system including selective serotonin reuptake inhibitors, an…
Interventions
- DrugMenopausal Hormone Therapy
Taken in accordance with standard clinical practice, administered for a minimum duration of eight weeks.
Location
- Mayo Clinic in RochesterRochester, Minnesota