Tumor-Derived Extracellular Vesicles for Noninvasive Molecular Classification of Kidney Cancer

Summary

This is a correlative (lab-based) study aiming to identify protein markers in urine extracellular vesicles (EVs) that can be used to develop non-invasive molecular tests for patients with renal cell carcinoma (RCC). Aim 1 will use urine collected previously in biorepository. Aim 2 will prospectively collect blood specimens pre and post nephrectomy.

Eligibility

Age range

Not specified

Sex

All

Healthy volunteers

No

Interventions

• Other
  Proteomic profiling of urinary EVs

  EV isolation and mass spectrometry.

• Procedure
  Blood sample collection

  Blood samples collected pre- and post-nephrectomy

Location