Evaluation Of Cardiovascular Health Outcomes Among Survivors 2 (ECHOS2)
St. Jude Children's Research Hospital
Summary
Childhood cancer survivors who received certain treatments are at a higher risk of developing heart problems in the future. This study is looking at ways to educate childhood cancer survivors about that risk and encourage them to receive a recommended heart screening test.
Description
Primary Objective: * To determine the efficacy of the Healthy Hearts eHealth intervention compared to standard of care for improving screening echocardiogram adherence in childhood cancer survivors. Secondary Objective * To determine the efficacy of the Healthy Hearts eHealth intervention compared to standard of care for improving mediators of screening echocardiogram adherence in childhood cancer survivors. After consenting, participants will complete a survey that will take about 15-20 minutes to complete. After this survey, they will be randomly assigned to participate in the Healthy He…
Eligibility
- Age range
- 26+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Childhood Cancer Survivor Study (CCSS) Participants * Age ≥26 years * Treated with cumulative doxorubicin equivalent anthracycline doses ≥100 mg/m2 with any/no radiation, or ≥15 Gy chest radiation with any/no anthracyclines * No history of cardiomyopathy * Has not had an echocardiogram in the previous 5 years * Has a history of successful completion of CCSS surveys * English-Speaking * Has not been enrolled in ECHOS-1 (pilot) Exclusion Criteria: • Currently participating in a long-term follow-up program that provides risk-based screening
Interventions
- BehavioralSurvivorship Care Plan + Educational Materials (delivered via CIAS platform)
Participants receive a personalized survivorship care plan and educational materials about cardiomyopathy risk and screening recommendations. Materials are delivered via the CIAS platform and include infographics, treatment summaries, and general information about screening.
- BehavioralHealthy Hearts eHealth Program
Participants receive the same SOC materials plus a tailored, interactive eHealth intervention delivered via the CIAS platform. This includes avatar-led motivational interviewing (MI), survivor video vignettes, interactive modules addressing perceived barriers, self-efficacy, and goal setting. The intervention is designed to mimic MI counseling in a scalable format.
Location
- St. Jude Children's Research HospitalMemphis, Tennessee