TriHealth Inc.
We are looking to see if patients using both topical testosterone and estrogen will have a greater improvement in pain with vaginal penetration compared to those using topical estrogen alone.
You are being asked to take part in this research study because you have vulvodynia. Vulvodynia refers to pain in the female vestibule. The vestibule is the area that encircles the vaginal opening and the urethra opening. One of the symptoms of vulvodynia is pain with intercourse. The purpose of this research study is to determine if using estrogen cream versus a combined cream with estrogen and testosterone helps decrease your pain with intercourse. Multiple studies have been conducted looking at the use of combined cream with estrogen and testosterone to treat vulvodynia. However, none of…
Inclusion Criteria: * 18 years or older * Patients with vulvodynia who present with pain (with vaginal penetration) rating score of 4 or greater Exclusion Criteria: * Active vaginal infection * Pregnancy * Breast-feeding * Taking anti-androgenic medication (finasteride, dutasteride) * Using any other topical hormones to the vulva or vagina
0.01% Estradiol cream, 1g to be applied to the vestibule twice daily for 12 weeks
0.01% Estradiol and 0.1% testosterone cream, apply 1g to the vestibule twice daily for 12 weeks
Arctuva estimate
Verify or correct the compensation shown for this listing.