A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Once Weekly Eloralintide in Adult Participants With Obesity or Overweight, and Type 2 Diabetes
Eli Lilly and Company
Summary
The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants with overweight or obesity and type 2 diabetes. Participation in the study will last about 75 weeks.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Have type 2 diabetes * Are on stable treatment for type 2 diabetes for at least 90 days prior to screening * Have a BMI ≥ 27 kg/m2 * Have a stable body weight (\<5% body weight change) for 90 days prior to screening Exclusion Criteria: * Have a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed \>1 year before screening) * Have a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy acceptable if device removal was more than 6 months prior to screening)…
Interventions
- DrugEloralintide
Administered SC
- DrugPlacebo
Administered SC
Locations (159)
- Birmingham Clinical ResearchBirmingham, Alabama
- Cullman Clinical TrialsCullman, Alabama
- Tucson Clinical Research InstituteTucson, Arizona
- San Fernando Valley Health InstituteCanoga Park, California
- AMCR InstituteEscondido, California
- NorCal Medical Research, IncGreenbrae, California