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261 recruiting studies matching your filters

Efficacy, Safety and Pharmacokinetics of Cagrilintide s.c. 2.4 mg as Monotherapy and in Combination With Semaglutide s.c. 2.4 mg (CagriSema) Once Weekly for Weight Management in Chidren and Adolescents With Overweight or Obesity

This study will look at how well CagriSema and cagrilintide help children and adolescents with excess body weight lose weight. The study has 2 parts: main and …

OverweightObesity

Estimated

~$10 – $7,500

Novo Nordisk A/SNCT07253285

Phase 2

Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)

Background: Artificial sweeteners like sucralose are found in many foods and drinks. Sucralose might affect hormones and cause health changes. Objective: To…

Healthy VolunteersOverweight

Estimated

~$10 – $5,625

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NCT03407079

Observational

Hydration Intervention to Address Dehydration Associated With Use of GLP-1 Based Medications

This is a 17 - week study consisting of a one - week run - in period and a 16 - week intervention. The 16 - week pilot interventions aims to increase hydration…

Obesity & OverweightType 2 DiabetesType 2 Diabetes (Adult Onset)+2 more

Estimated

~$10 – $6,250

State University of New York at BuffaloNCT07641361

Phase 1

A Single Center, Multiple Dose, Randomized, Placebo-controlled Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects

Randomized, Placebo-controlled Study to determine the safety and tolerability of multiple oral doses of TIX100 administered daily for 28 days to otherwise heal…

Health Adult SubjectsObesity & Overweight

Estimated

~$10 – $8,750

TIXiMED, Inc.NCT07675590

Phase 1

A Phase 1, Open Label, Parallel Group Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics of Ribupatide in Healthy Participants and in Participants Living With Severe Renal Impairment or End Stage Kidney Disease

The primary objective of the study is to estimate the PK parameters of ribupatide in participants with severe renal impairment or end-stage kidney disease (ESK…

End Stage Renal DiseaseRenal ImpairmentObesity+1 more

Building Capacity in Precision Nutrition to Address Obesity and Diabetes in Underserved Communities

This randomized controlled trial will evaluate the effectiveness of a culturally sensitive precision nutrition intervention for improving obesity- and diabetes…

Obesity & OverweightPrediabetes

Estimated

~$10 – $6,250

Prairie View A&M UniversityNCT07850531

Phase 3

Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Type 2 Diabetes (AMAZE 2)

The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and type 2 diabetes. Th…

Diabetes MellitusOverweightObesity

Estimated

~$10 – $7,500

Novo Nordisk A/SNCT07533175

Observational

Effects of a Two-Week Stair-Climbing "Exercise Snacks" Intervention on Body Composition, Cardiovascular Fitness, and Metabolic Responses in Overweight and Obese Adults: A Pilot Study

This pilot study will evaluate whether brief bouts of stair climbing performed throughout the day for two weeks can improve metabolic health, cardiovascular fi…

Overweight , Obesity

Estimated

~$10 – $6,250

St. Louis UniversityNCT07849439

Observational

Comparing the Efficacy and Safety of the EndoZipTM System and Apollo Endoscopic Sleeve Gastroplasty (ESG), Followed by Behavioral Modifications, in Obese Patients Who Have Not Achieved Weight Reduction Through Non-surgical Methods.

evaluation of the EndoZip system procedure compared to the Apollo ESG procedure in obese patients.

ObesityOverweight

Estimated

~$10 – $8,750

Nitinotes Surgical Ltd.NCT07090005

Phase 2

A Phase 2 Dose-Finding Study to Assess the Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

Obesity is a condition where a person has excessive body fat, defined by a body mass index (BMI) of 30 kg/m2 or higher. The goal of this study is to evaluate t…

Semaglutide, Weight Loss, And Intrauterine Therapy For Fertility-Sparing And Conservative Treatment For Endometrial Atypical Hyperplasia And Early-Stage, Grade 1 Endometrioid Endometrial Cancer

The goal of this clinical trial is to learn if a combination treatment of a hormonal intrauterine device (LNG-IUD), semaglutide, and a structured weight loss p…

Endometrial Atypical HyperplasiaEndometrial Atypical Hyperplasia/Endometrioid Intraepithelial NeoplasiaEndometrial Cancer Stage I+3 more

Estimated

~$10 – $6,250

The Methodist Hospital Research InstituteNCT07820358

Phase 2

A Phase 2, Randomized, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of Olatorepatide, a GLP-1/GIP Receptor Agonist, With Different Doses and Drug-Titration Algorithms in Participants Living With Overweight or Obesity

This study will test an experimental drug called olatorepatide ("study drug") to determine how safe and effective this drug is compared to placebo and how easi…

Overweight or Obesity

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07685808