University of California, San Francisco
The purpose of this study is to improve the diagnosis and prediction of recovery after traumatic brain injury (TBI) in adults age 65 years and older. The study will follow older adults who present to the emergency department after TBI, as well as matched control participants, and will measure clinical features, brain imaging, and blood-based biomarkers over 12 months to understand how recovery changes over time. Researchers will examine how pre-injury health, brain structure, and biological markers are related to disability and cognitive outcomes after TBI. Information from this study will be used to develop age-appropriate tools to better diagnose TBI and estimate long-term outcomes in older adults.
TRACK-GERI/VA TBI PATIENT INCLUSION/EXCLUSION CRITERIA Inclusion Criteria: 1. Age 65 years and older, no upper age limit 2. Reliable report or physical evidence of head trauma 3. Injury occurred \<72 hours ago (within 14 days of injury for TRACK-VA TBI patients) 4. Acute brain CT for clinical use 5. Fluency in English/Chinese (UCSF only) 6. Ability to obtain informed consent from subject or legally authorized representative 7. Ability to be co-enrolled with a study partner who meets Study Partner enrollment criteria Exclusion Criteria: 1. Significant polytrauma that would interfere with fo…
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