A Randomized, Open-Label, Controlled Study to Evaluate the Effects of a Prebiotic Soda on Glycemic Control in Adults With Glucose Dysregulation
Olipop, PBC
Summary
The main objective of this study is to evaluate the chronic effects of replacing traditional non-diet soda with a prebiotic soda on biomarkers associated with glycemic control in adults with glucose dysregulation who are habitual consumers of traditional soda.
Description
The primary aim of this clinical trial is to evaluate the effects of replacing traditional non-diet soda with a prebiotic soda (i.e., OLIPOP) over an 8 week period on markers of glucose (blood sugar) control in adults with glucose (blood sugar) dysregulation. Participants (n=224) will be habitual consumers of traditional non-diet sodas, consuming on average 2-3 servings of non-diet soda daily. Participants will be randomized to either an active control group (continued habitual traditional non-diet soda intake, 2 - 3 servings/day) or a behavioral intervention group (OLIPOP prebiotic soda, 2 c…
Eligibility
- Age range
- 30–70 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Able to provide informed consent * Willing to comply with all study procedures * Male or female, ages 30 - 70 years old * Habitual consumers of traditional non-diet soda (average intake 2 - 3 servings (24-36 fl. oz)/daily in a typical month, representing usual dietary pattern) * BMI between 25 - 35 kg/m² * Fasting plasma glucose between 100 - 125 mg/dL or hemoglobin A1c between 5.7% - 6.4% * Low habitual dietary fiber intake, assessed using a qualitative fiber intake screening questionnaire administered at pre-screening * Willing to maintain stable tobacco/nicotine use h…
Interventions
- BehavioralPrebiotic Soda
Participants will replace traditional non-diet sodas in their diet with a prebiotic soda (OLIPOP). Participants will consume 2 cans/day (24 fl. oz/day) that will add 12 g dietary fiber/day to their diet.
- BehavioralActive Control
Participants will continue to consume their habitual intake (on average 2-3 servings/day) of traditional non-diet soda.
Location
- People ScienceLos Angeles, California