Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology
Palo Alto Veterans Institute for Research
Summary
This is a pilot study to evaluate the feasibility, image quality, and procedural utility of a novel spectral CT technique using Canon Medical's 4D CT system during image-guided interventional oncology procedures
Description
The aims of this study are: 1. Demonstrate the feasibility of acquisition and image quality of intra-arterial spectral CT images obtained during mapping arteriography prior to trans arterial radioembolization (TARE) for liver cancer treatment. 1. Assess the procedural utility of Spectral CT images as part of the TARE workflow, such as hepatopulmonary shunt fraction estimation, lesion identification, prediction of tumor: normal liver (T:N) dose ratio, and dose distribution 2. Investigate the feasibility, safety, and image quality of Spectral CT images obtained during tumor ablation. 2.…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion criteria: 1. Age \> or = 18 years 2. Tumor in an area without prior surgical or ablative therapy 3. At least 1 tumor greater than 1.5 cm in greatest diameter Exclusion criteria: 1. Not eligible for indicated procedure. 2. BMI \> 35 3. Prior surgery.
Location
- VA Palo Alto Healthcare SystemPalo Alto, California