Scientific Proof of Music Therapy's Impact on Alzheimer's Disease
University of Central Florida
Summary
The purpose of this study is to scientifically validate the impact of music therapy on Alzheimer's disease (AD) by analyzing molecular biomarkers in salivary exosomes. Exosomes are extracellular vesicles that carry molecular signals from brain cells, providing a non-invasive method to assess physiological changes.
Description
Music therapy has long been recognized as a beneficial intervention for individuals with Alzheimer's disease (AD), with evidence supporting improvements in mood, cognitive function, and behavioral symptoms. However, despite widespread clinical use, the biological mechanisms underlying these benefits remain poorly understood. Most studies on music therapy in AD have relied on behavioral observations and qualitative assessments, lacking objective, molecular-level validation. Recent advancements in exosome research have opened new possibilities for non-invasive biomarker analysis. Exosomes, small…
Eligibility
- Age range
- 50+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * 50 years old or older. * 20 adults with no mild-cognitive impairment * 20 adults with mild-cognitive impairment * 20 adults with Alzheimer's disease/ dementia. * participant or the participant's legally authorized representative must be able to read or speak English and agree to comply with study procedures. * pregnant women may chose to participate Exclusion Criteria: * 49 years and younger * prisoners * unable to understand English and provide consent
Interventions
- OtherMusic intervention
UCF music concert where the participants will listen to symphonic, classical music for 1 hour.
Location
- University of Central FloridaOrlando, Florida