Flex Appeal: A Prospective Randomized Controlled Trial Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia (MUA)
Duke University
Summary
The purpose of this study is to determine if changing the type of anesthesia improves the outcomes of manipulation and pain control after the procedure. The study will compare a spinal anesthesia with a general anesthesia, to see if there is a better outcome from either anesthesia type.
Eligibility
- Age range
- 18–75 years
- Sex
- All
- Healthy volunteers
- No
Inclusion: 1. Patients ≥18 years presenting for a manipulation of knee joint under anesthesia. 2. ASA Classification I - III. 3. English speaking patients. Exclusion: 1. ASA 4 or 5 2. Daily chronic opioid use (over 3 months of continuous opioid use). 3. Inability to communicate pain scores or need for analgesia. 4. Infection at the site of block placement 5. Age under 18 years old or greater than 75 years old 6. Pregnant women (as determined by point-of-care serum bHCG) 7. Intolerance/allergy to local anesthetics 8. Weight \<50 kg 9. Suspected, or known addiction to or abuse of illicit drug…
Interventions
- ProcedureSpinal Anesthesia
Administration of spinal anesthesia for knee manipulation.
- ProcedureGeneral Anesthesia
Administration of general anesthesia for knee manipulation.
- DrugPropofol
Patients undergoing general anesthesia will receive an induction dose of propofol that will be titrated to effect, and airway support as needed until the patient is appropriately anesthetized for the procedure as determined by the anesthesia and surgical care teams.
- DrugChloroprocaine
Patients undergoing spinal anesthesia will receive a spinal injection under standard aseptic technique, with 45mg chloroprocaine.
Location
- Duke University Health SystemDurham, North Carolina