A 12-Week Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

Colgate Palmolive

Summary

To evaluate the efficacy of a stannous fluoride toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

Eligibility

Age range: 18–70 years
Sex: All
Healthy volunteers: Yes

Detailed criteria

Inclusion Criteria: * Signed Informed Consent Form. * Male and female subjects aged 18-70 years, inclusive. * Availability for the twelve-week duration of the clinical research study. * Good general health based on the opinion of the study investigator * Minimum of 20 permanent natural teeth (excluding third molars). * Initial gingivitis index of at least 1.0 as determined by the use of the Loe and Silness Gingival Index. * Initial mean plaque index of at least 0.6 as determined by Rustogi Modification of the Navy plaque index. Exclusion Criteria: * Presence of orthodontic appliances; * Pre…

Interventions

Drug
0.454%Stannous fluoride toothpaste
toothpaste
Drug
0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe
mouthwash
Drug
0.76% Sodium Monofluorophosphate (Na MFP) toothpaste
toothpaste
Drug
0.022% Sodium Fluoride mouthwash
mouthwash

Location

Consumer Research Consulting, LLC
Melbourne, Florida