Liquid Biopsy in Glioblastoma Treated With Chemoradiation and an Oxygen Therapeutic

NuvOx LLC

Summary

The goal of this sub-study of the RESTORE trial is to identify biomarkers associated with tumor hypoxia, identify biomarkers that differentiate pseudoprogression from true progression, and correlate biomarkers with clinical outcomes.

Description

Blood samples for liquid biopsy will be collected at the same time as the scheduled blood draws in the RESTORE study and analyzed by FYR Diagnostics.

Eligibility

Age range: 18+ years
Sex: All
Healthy volunteers: No

Detailed criteria

Inclusion Criteria: * Subjects must be enrolled in the RESTORE study (NCT03862430) and provide written informed consent for the RESTORE LB sub-study

Locations (4)

Center for Neurosciences
Tucson, Arizona
Yale Cancer Center
New Haven, Connecticut
Saint Luke's Cancer Institute
Kansas City, Missouri
Duke University Medical Center
Durham, North Carolina