The Cardiometabolic Impact of Non-Nutritive Sweeteners in Young Adults With Type 1 Diabetes
Medical College of Wisconsin
Summary
This project will apply a novel non-nutritive sweetener (NNS) dietary assessment tool with measurement of circulating NNS levels in a pediatric population, allowing correlation of NNS exposure to clinically meaningful cardiometabolic health outcomes.
Description
The purpose of this project is to learn how NNS affects the health of the blood vessels. Type 1 diabetes (T1D) is an autoimmune disease that requires lifelong dependence on prescribed insulin. Scientists know that if an individual has T1D, they are at greater risk of having cardiovascular disease than people who do not have diabetes. To help manage diabetes, individuals may talk with their doctor about adjusting what they normally eat or drink. Doctors typically ask that individuals avoid foods and drinks with lots of sugar in them. In response to this, individuals might drink diet drinks or…
Eligibility
- Age range
- 15–24 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Aged 15-24 years 2. Clinical diagnosis of type 1 diabetes, requiring insulin therapy, of ≥ 1 to \< 10 years duration. 3. Last available HbA1c ≤ 8.5% (obtained by chart review in Children's Wisconsin Diabetes Clinic patients or verbally by individuals not receiving diabetes care at Children's Wisconsin) 4. Current use of an FDA approved automated insulin delivery (AID) system 5. Willing to consume a 12 ounce Gatorade G Zero Glacier Cherry drink in less than 10 minutes 6. Willing and able to give informed consent or have parent or legal guardian provide informed consent i…
Interventions
- Dietary SupplementCherry Sports Drink
12 oz bottle (1 1/2 cups) of Gatorade G Zero Glacier Cherry™ Sports Drink
Location
- Medical College of WisconsinMilwaukee, Wisconsin