Intubating Conditions Based On The Ratio Between The Twitch Amplitude And Reference Twitch Amplitude: A Randomized, Prospective, Clinical Trial

Mayo Clinic

Summary

The purpose of this study is to determine the maximum ratio of the twitch amplitude (T1) to the reference twitch (Tref) amplitude (T1/Tref) that provides excellent intubating conditions.

Eligibility

Age range: 18+ years
Sex: All
Healthy volunteers: No

Detailed criteria

Inclusion Criteria: * Age \> or = 18 years old * Patients willing to participate and provide an integrated, informed consent Exclusion Criteria * Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury. * Patients with systemic neuromuscular diseases such as myasthenia gravis. * Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment requiring dialysis or end-stage liver disease. * Patients…

Interventions

Device
Twitch amplitude <0.1
(T1/Tref) \<0.1
Other
Twitch amplitude <0.3
(T1/Tref) \<0.3
Other
Twitch amplitude <0.5
(T1/Tref) \<0.5

Location

Mayo Clinic in Florida
Jacksonville, Florida

Intubating Conditions Based On The Ratio Between The Twitch Amplitude And Reference Twitch Amplitude: A Randomized, Prospective, Clinical Trial

Summary

Eligibility

Interventions

Location

Run this study?

Details

Conditions