Impact of a Multiplex Respiratory PCR Test on Outcomes for Patients Presenting With Respiratory Illness in the Urgent Care Setting: A Hybrid-Effectiveness Quasi-Experimental Trial
BioMérieux
Summary
This research study will use a hybrid effectiveness-implementation type 1 design to assess effectiveness of the Spotfire R/ST assay in the urgent care setting. A hybrid effectiveness-implementation type 1 study primarily focuses on the effectiveness of an intervention (e.g., use of Spotfire R/ST) but also simultaneously allows for the collection of data on the barriers and facilitators of implementing the Spotfire R/ST test in the real-world urgent care setting.
Description
Antimicrobial resistance (AMR) is a critical public health challenge and a significant global burden. In the United States, most antibiotics are prescribed in outpatient settings, with suspicion or confirmation of a respiratory infection serving as a primary driver of unnecessary antibiotic use. This use is deemed inappropriate in approximately 30% of cases. This estimate differs based on setting and patient population. For example, a study assessing antibiotic use in a Veterans Affairs (VA) hospital demonstrated that 64.2% of patients received unnecessary antibiotics, with diagnoses such as b…
Eligibility
- Age range
- 1+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patients older than 1 year * Patients presenting with signs and symptoms of acute respiratory illness including but not limited to bronchitis, bronchiolitis, rhinitis, pharyngitis, tonsillitis, and laryngitis * First visit for respiratory indication within the study period Exclusion Criteria: * Patients younger than 1 year * Patients for which there is a clinical suspicion of pneumonia (i.e., severe illness on presentation requiring hospitalization or not eligible for urgent care) * Patients experiencing symptoms for \> 10 days * Patients with significant respiratory c…
Interventions
- DeviceSPOTFIRE R/ST Diagnostic Test
At the intervention site, subjects meeting the inclusion and exclusion criteria, and who provide consent to participate in the study, will have a respiratory sample tested on the SPOTFIRE R/ST Panel, with results used by the treating clinician to guide management . At the end of the visit, enrolled patients will take a satisfaction survey, based on the AHRQ-validated CAHPS survey
Locations (2)
- American Family Care - GardendaleGardendale, Alabama
- American Family Care - GroveHoover, Alabama