Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study
University of California, San Francisco
Summary
This study is being conducted to assess two imaging methods-central microperimetry and radial OCT (Optical Coherence Tomography)-in patients with Geographic Atrophy (GA) or those who are at risk of developing this condition. The study team is trying to determine whether these methods can provide more accurate measurements of GA progression toward the foveal center, the central part of the retina responsible for your sharpest, most detailed vision.
Eligibility
- Age range
- 55+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Subjects must be 55+ years of age Subjects in the "Intermediate AMD Observation Arm" must have intermediate age-related macular degeneration in one eye Subjects in the "GA Observation Arm", "GA Continuing Treatment Arm", and "GA Treatment Arm" must have non-central GA (defined as GA has not involved the center point of the fovea) and at least 1% GA in the central 1 mm zone. Exclusion Criteria: * Subjects with central involvement of GA. Central involvement is defined as geographic atrophy involving the foveal center point. Subjects with a baseline size of GA \> 17.5mm…
Interventions
- Diagnostic TestOptical coherence tomography
High-resolution imaging method used to evaluate the structure of the retina
- Diagnostic TestMicroperimetry
A functional test that maps retinal sensitivity by measuring how well you can detect lights in different areas of your vision.
Location
- University of California, San FranciscoSan Francisco, California