Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Summary
The goal of this study is to learn if an online computerized training program improves processing speed, attention, and working memory in children with a primary brain tumor during and after active cancer treatment. The main questions it aims to answer are: 1. Is the cognitive intervention feasible to administer to children with brain tumors during and after cancer treatment?, 2. Is the cognitive intervention acceptable to children and caregivers?, and 3. Does the cognitive intervention improve neuropsychological functioning? There is no comparison group for this study. Participants will: 1. Complete an online computerized cognitive training program for approximately 15 minutes per day, 5 days a week, for 8 weeks; 2. Have weekly check-ins with the cognitive coach, 3. Complete a survey at the end of the cognitive training program, and 4. Complete pre- and post- neuropsychological testing.
Eligibility
- Age range
- 5–25 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Diagnosis of a primary brain tumor, 2. Children and young adults 5 to 25 years of age at the time of enrollment, 3. Within five years of initial brain tumor diagnosis, 4. Receiving care through the Johns Hopkins neuro-oncology program. Exclusion Criteria: 1. Significant visual, hearing, motor, or cognitive impairment that precludes participation in computerized cognitive training program; 2. Acute medical status (e.g., significant risk for mortality within 3-months of diagnosis).
Interventions
- BehavioralOnline computerized cognitive training intervention focused on processing speed.
This online cognitive training program aims to improve processing speed through computerized cognitive exercises. Participants will complete approximately 15 minutes of training, 5 days per week for 8 weeks. Weekly check-ins with a cognitive coach will assist with engagement and problem solve any barriers.
Location
- Kennedy Krieger InstituteBaltimore, Maryland