Piloting an Intervention to Improve Adjuvant Endocrine Therapy Adherence in Patients With Breast Cancer in Rwanda
Dana-Farber Cancer Institute
Summary
This study aims to evaluate a multi-modal intervention designed to improve adherence to adjuvant endocrine therapy (AET) among patients with ER-positive breast cancer in Rwanda. The intervention includes educational, behavioral, and reminder components, and will be assessed for feasibility and impact on medication adherence.
Description
This is a randomized study evaluating a light-touch, multi-modal medication adherence support package designed to improve adherence to adjuvant endocrine therapy in adults with confirmed ER-positive breast cancer undergoing curative intent treatment. Eligible participants will be within 6-36 months of adjuvant endocrine therapy initiation and will be randomized to receive either standard care or the medication adherence support package, which includes a one-time educational video, a symptom monitoring card, and weekly one-way text message reminders. The research study procedures include: scre…
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: * Female patients * Age 18 or older * Pathologic confirmation of ER-positive breast cancer * Clinical or radiographic confirmation of disease localized to the breast and regional lymph nodes * Within 6-36 months of starting AET * Have a cellphone capable of receiving text messages. * Are currently receiving AET at Butaro or satellite clinics. Exclusion Criteria: * Unwilling/Unable to participate * Unable to comprehend study languages (English or Kinyarwanda) * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Prisoners * Pregn…
Interventions
- BehavioralEducational video
One-time educational video
- BehavioralSymptom monitoring card
Symptom monitoring card
- BehavioralText reminders
Weekly one-way text reminders
Locations (4)
- Brigham and Women's HospitalBoston, Massachusetts
- Boston Children's HospitalBoston, Massachusetts
- Dana-Farber Cancer InstituteBoston, Massachusetts
- Butaro Cancer Center of ExcellenceButaro, RN8