Evaluating a Digital Intervention to Improve Resilience and Reduce Stress in Stanford Populations (SIER Study)
Stanford University
Summary
High-achieving academic and entrepreneurial populations face elevated risks of chronic stress, anxiety, and burnout. These populations often underutilize mental health services due to stigma, time constraints, or accessibility issues. Digital interventions provide an opportunity to deliver evidence-based stress and resilience support at scale. The WONE (Walking on Earth, Ltd.) platform integrates personalized stress-resilience assessments, behavioral science micro-interventions, and optional wearable data feedback. This project aims to evaluate the feasibility, engagement, and preliminary efficacy of the WONE digital intervention in multiple Stanford-affiliated cohorts.
Description
Primary Objective To evaluate whether engagement with the WONE app improves resilience, emotional well-being, and stress management outcomes among Stanford-affiliated adults. Secondary Objective To evaluate the feasibility of wearable-device integration. Rationale for Two-Phase Structure This protocol includes two sequential studies. 1. Phase 1 (Pilot): A single-arm feasibility pilot designed to assess acceptability of the WONE digital intervention, verify that onboarding, survey workflows, and data capture function smoothly, and identify any usability issues before running a randomized tri…
Eligibility
- Age range
- 18–65 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. Aged between 18 and 65 years with Stanford affiliation 2. English proficiency with the ability to read, write, and complete surveys in English 3. Smartphone with internet access 4. Willingness to complete surveys and app activities 5. Resides in the US 6. Stanford affiliation 7. Wearable device for Phase 1 Pilot Study Exclusion Criteria: 1. Severe psychiatric instability, defined as any of the following self-reported on the pre-enrollment screener: 1. Psychiatric hospitalization for a mental health crisis in the past 12 months. 2. Current mental health symptoms…
Interventions
- BehavioralIntervention WONE App (full Version)
The Intervention WONE app (Full version) has the following features: * AI coaching for personalized support * Educational articles * Live sessions * On-demand session recordings * WONE Index assessment and tracking * Wearable device connection (optional) and wearable-derived scores and metrics The control WONE app (limited version) has no above features, only has push notifications for participants to complete assessments.
Location
- Stanford School of MedicineStanford, California