Memorial Sloan Kettering Cancer Center
The researchers are doing this study to find out whether a high-fiber plant-based diet (HFPBD) can improve quality of life for people with CH. A HFPBD includes foods that are mainly from plants (for example, fruits,vegetables, nuts, beans, and whole grains). The researchers will measure quality of life by having participants complete questionnaires/surveys.
Inclusion Criteria: * Patients must have confirmed clonal hematopoiesis via next generation sequencing (NGS) of blood or bone marrow biopsy sample * Patients with clonal cytopenias of undetermined significance (CCUS) are eligible if a bone marrow biopsy is done to exclude other causes. * Variant allele frequency must be ≥2% for mutation as measured by (NGS) * Treatment at MSK or at sites listed below that uses EPIC for electronic medical records and willing to share records with MSK through EPIC's care everywhere or through MSK's shared care network. If not meeting this criterion, decision to…
A meal service will ship 12 frozen prepared meals per week to your home.
Fermented foods will be encouraged on the diet. Fermented foods contain probiotics that help support a balanced gut microbiome and might improve overall digestion.
Patients will be recommended by research dietitian to take a weekly vitamin B12 supplement (at least 500 mcg weekly)
QOL will be measured with the EORTC QLQ C30