Salvaged Red Blood Cell Transfusion During Pancreatic Adenocarcinoma Operations
NYU Langone Health
Summary
The purpose of this study is to prospectively study the safety of salvage red blood cell (sRBC) transfusion during pancreatic surgery. Primary Objective: 1. To summarize rates and timing of septic adverse events (AE) for patients who receive sRBC or aRBC transfusions within 72 hours of peri-operative transfusion. 2. To summarize rates and timing of transfusion related AEs for patients who receive sRBC or aRBC transfusions within 72 hours of peri-operative transfusion. 3. To summarize rates and timing of AEs in the first 7 post-operative days. Secondary Objectives: 1. To summarize the number of units of aRBC transfused post operative day (POD) #0 after sRBC transfusion in the operating room. 2. To summarize the number of units of aRBC transfused POD#1-7 after sRBC transfusion the operating room, in the absence of overt post-operative hemorrhage.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Provision of signed and dated informed consent form. Able to understand their disease and the exploratory nature of sRBC transfusion during surgery for this histology. 2. Patient is 18 years of age or older 3. Patient has a diagnosis of cytologically or pathologically confirmed pancreatic adenocarcinoma 4. Patient has an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2 5. Patient has an American Society of Anesthesiologists (ASA) classification of physical health status of 1-4 6. Life expectancy of greater than six months 7. Hemoglobin \> 8.9 g/dl 8.…
Interventions
- DeviceThe Fresenius Kabi C.A.T.S®plus Continuous AutoTransfusion System
A cell salvage device will be utilized to collect all spilled blood during the course of the operative resection and vascular reconstruction.
Location
- NYU Langone HealthNew York, New York