Exosome-based Omic Signatures of Disease Activity in Cardiac Sarcoidosis (EXODACS)
Mayo Clinic
Summary
The purpose of this study is to develop a prospective cohort of patients with and without cardiac sarcoidosis as well as active and inactive disease to develop a prospective biobank from which exosome analysis of peripheral blood will derive unique biomarkers of disease activity in cardiac sarcoidosis.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria * Adults ≥18 years. * Patients referred to the Cardiac Sarcoid Clinic with a clinical suspicion or a previously confirmed diagnosis of cardiac sarcoidosis. * Undergoing FDG-PET as part of standard care. * Ability to provide informed consent. Exclusion Criteria • Inability to provide informed consent.
Interventions
- OtherExosome Analysis
Blood Samples will undergo exosome profiling using mass spectrometry and/or other discovery-based approaches
Location
- Mayo Clinic in RochesterRochester, Minnesota