City of Hope Medical Center
This clinical trial studies whether physiatry-led cancer prehabilitation can be used during systemic treatment before surgery (neoadjuvant systemic treatment \[NST\]) to improve function in stage III-IVA gynecologic cancer patients. Treatment of gynecologic cancers presents significant challenges to physical and mental health and patients often experience many challenges following treatment including sleep disturbance, extreme tiredness, sexual dysfunction, and bowel and urinary problems. Patients who have low functioning prior to surgery often have worse outcomes following surgery; however, services to support functional shortages often start after surgery. Physiatry-led cancer prehabilitation is a strategy aimed at reducing post-treatment functional challenges by improving physical and mental function before treatment. It involves physiatry, which is a medical specialty focused on function. Physiatry involvement in prehabilitation allows for the evaluation and management of co-existing conditions, medical supervision, and the coordination of complex plans involving multiple teams. Using physiatry-led cancer prehabilitation during NST may be an effective way to improve function in stage III-IVA gynecologic cancer patients.
PRIMARY OBJECTIVES: I. Determine feasibility based on adherence (\> 70%) across the key components-exercise (aerobic and resistance), nutrition, and mind/spirit practice-in \> 70% of enrolled patients for the 28-day period immediately prior to surgery. II. Evaluate feasibility via enrollment rate \> 50% of eligible patients. SECONDARY OBJECTIVES: I. Evaluate physical measures: Six Minute Walk Test, Duke Activity Status Index, 30-second Sit to Stand, Short Physical Performance Battery, Patient Reported Outcomes Measurement Information System (PROMIS) Cancer Function Brief Three Domains (3D)…
Inclusion Criteria: * PATIENT: Documented informed consent of the participant * PATIENT: Willingness to comply with a physiatry consultation, start a tailored training program, and follow-up assessments * PATIENT: Age: ≥ 18 years * PATIENT: Able to read and write in English * PATIENT: A diagnosis of stage III-IVA gynecologic cancer planned for NST * PATIENT: Plan to start NST at City of Hope Orange County * HEALTHCARE TEAM: Documented informed consent of the participant * HEALTHCARE TEAM: Willingness to complete the Healthcare Worker Survey * HEALTHCARE TEAM: ≥ 18 years old * HEALTHCARE TEAM:…
Receive written prehabilitation education materials
Follow and meet prehabilitation goals
Ancillary studies
Receive tailored multidisciplinary referrals
Attend cancer physiatry consultation
Receive resistance bands, nutritional guidance sources, and tips and resources
Ancillary studies
Receive starter prescription