Stanford University Microbiome Bank
Sean Spencer
Summary
This protocol establishes a centralized stool donor bank and research platform to support microbiota transplantation therapy (MTT) for microbiota-mediated diseases. The study will characterize donor microbiome, metabolite, immune, and dietary profiles.
Description
Eligible participants will undergo comprehensive baseline screening including physical examination, infectious disease testing, and health history assessment. Those who qualify will enter an active donation period of up to 12 months, during which they will provide stool samples at a frequency ranging from once per month to once per week, depending on their availability. In addition to stool collection, participants will provide biospecimens including blood draws (for infectious disease and metabolic monitoring), saliva samples, and small intestinal fluid samples collected using an ingestible…
Eligibility
- Age range
- 18–80 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Any person aged 18-80 years of age, inclusive at the time of signing the consent * In good general health as evidenced by medical history * Ability to travel to donation facility on a weekly basis * Residence within 5 miles of Stanford Campus * For females of reproductive potential: use of highly effective contraception for at least 1 month prior to screening and agreement to use such a method during study participa…
Interventions
- OtherMicrobiome bank
This is an observational study with no interventions.
Location
- Stanford UniversityPalo Alto, California