Determining the Success of a Urine Metabolite Point-of-care Colorectal Cancer Early Diagnosis Test in Africa
Memorial Sloan Kettering Cancer Center
Summary
The purpose of this study is to find out whether a urine test can detect colorectal cancer (CRC) and precancerous polyps in participants living in Ghana, Tanzania, and South Africa.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patient presents with one of the following: * Patients with symptoms of CRC (such as rectal bleeding for a week) -OR- * Patients who present for a screening colonoscopy -OR- * Has received one of the following within 3 weeks of the planned urine collection * Patients with a pathologic diagnosis of CRC either by colonoscopy or resection specimens -OR- * Patients with colonoscopy demonstrating adenomatous polyps -OR- * Patients with colonoscopy demonstrating no colon or premalignant or malignant pathology * Age ≥ 18 * Willingness to participate in the s…
Interventions
- Diagnostic Test3-metabolite biosensor
3-metabolite biosensor will identify participants with colorectal cancer (CRC) and precancerous polyps
Locations (4)
- Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York
- Korle Bu Teaching Hospital (Data Collection Only)Accra
- Wits Donald Gordon Medical Centre (Data Collection Only)Johannesburg
- Kilimanjaro Christian Medical Centre (Data Collection Only)Moshi