Naturalistic Neuroimaging for Neurosurgical Brain Mapping
Brigham and Women's Hospital
Summary
We are doing this research to compare a new type of functional MRI (fMRI) called naturalistic viewing (also called movie watching) to standard clinical fMRI techniques. Standard clinical fMRI currently uses multiple tasks such as reading and responding to words or sentences to determine which areas of the brain are responsible for language. Surgeons can use this information to help plan brain surgeries. We hope to determine if the movie-watching fMRI is equivalent or better than the standard task-based fMRI. If so, it could be useful for planning patients' surgeries in the future, without the need for multiple tasks.
Eligibility
- Age range
- 21–70 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Any sex, age between 21 to 70 years; * Known or suspected glioma (lesion) of the brain; * English speaking; * Patients with clinical fMRI scheduled (or pending scheduling) for presurgical planning at BWH ordered by a BWH clinician; * Passes prescreening and standard of care screenings for 3 Tesla MRI; * Willing to participate in the additional study scan and neuropsychological assessment visit; * Informed consent form signed by the subject or legally acceptable representative. Exclusion Criteria: * Contraindications to MRI: Note: MRI screening will be performed by radi…
Interventions
- OtherFunctional magnetic resonance imaging (fMRI)
Functional magnetic resonance imaging (fMRI) is a type of non-invasive imaging that measures blood oxygen level-dependent (BOLD) signal changes in the brain when a task is performed (such as reading) or BOLD signal changes during resting or watching naturalistic stimuli (such as movie clips).
- BehavioralNeuropsychological Assessments
Neuropsychological assessments are standardized tests used to evaluate cognitive, behavioral, and emotional functions that reflect the performance of different brain systems. These tests can be on paper or on a computer.
Location
- Brigham and Women's HospitalBoston, Massachusetts