Effect of Female Life Stage on Rehydration With Water vs. an Electrolyte Solution After Overnight Fast/Fluid Restriction
PepsiCo Global R&D
Summary
Female life stages including premenopausal, perimenopausal, postmenopausal, are characterized by changing concentrations and patterns of hormones. The premenopause stage represents the reproductive years with normal menstrual cycles lasting between 21-35 days. The perimenopause stage is the beginning of the menopause transition and can last up to 10 years. During this transition, menstrual cycles become longer and irregular in length (7 days or longer). After 12 consecutive months with no period, the transition is complete into the postmenopause stage. Hormones that change across the lifespan are known to influence systems that regulate thirst, fluid balance, and sodium balance. Yet, fluid balance across life stages remains poorly understood, with no direct comparisons across all three life stages. The purpose of this study is to evaluate the effect of female life stage on rehydration with water and electrolyte solution after overnight fast and fluid restriction
Eligibility
- Age range
- 18–60 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * • Sex assigned female at birth. * Recreationally active (engaged in light to moderate-intensity, intermittent, or steady-state exercise at least 3 days per week for at least 30 min at a time) * Age 18-60 years, within the following life stage ranges specified below: * Premenopausal: * 18-35 years * Self-report regular spontaneous menstrual cycle length (21-35 days) for the past 2 menstrual cycles * Menstrual cycle length \< 7 days variation in consecutive cycles * Perimenopausal: * Perimenopause: 35-55 years * If tracking cycles: self repor…