Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy of HIV PrEP and STI PEP for Young Men
HIV Prevention Trials Network
Summary
Individual-Level Randomized Controlled Trial of an Integrated Strategy of HIV pre-exposure prophylaxis (PrEP) and sexually transmitted infection (STI) post-exposure prophylaxis (PEP) for Young Men
Description
This study will test a suite of mHealth tools to increase HIV pre-exposure prophylaxis (PrEP) uptake and adherence among young men in communities most affected by the HIV epidemic and evaluate the uptake, adherence, and acceptability of doxycycline for sexually transmitted infection (STI) post-exposure prophylaxis (doxy-PEP).
Eligibility
- Age range
- 18–29 years
- Sex
- Male
- Healthy volunteers
- Yes
Inclusion Criteria: 1. Men ages 18 - 29 years 2. Men who are in communities most affected by the HIV epidemic 3. Willing and able to provide informed consent 4. Reports having anal sex with men in the last 6 months 5. Have certain risk factors for HIV acquisition, defined as any of the following in the past 6 months: 1. Any condomless anal sex with a man; not including within a monogamous relationship with an HIV-negative partner or an HIV-positive partner who is virally suppressed 2. Reporting 2 or more male partners, regardless of condom use 3. Reporting gonorrhea, chlamydia, or s…