Oxygen Delivery in CPAP and Its Relationship With Regional Lung Ventilation in Preterm Infants
University of Arkansas
Summary
With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP). To gain more information on how much oxygen is actually delivered to the baby from the nCPAP machine.
Description
This study will tell more about a specific method of breathing support used frequently with preterm babies called nasal continuous positive airway pressure (nCPAP). It helps the baby breathe by providing air pressure and a certain amount of oxygen. It is very important for the baby's health to provide only as much oxygen as they need. With this study, it is expected to learn if the amount of oxygen ordered by a doctor on the nCPAP machine changes when it reaches the baby's airway, and if the amount of oxygen changes depending on how much air pressure the doctor provides. The answers to these…
Eligibility
- Age range
- Not specified
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Gestational age at birth must be less than 35 weeks of completed gestation as documented in the subject's initial history and physical * The infant must be stable while receiving nasal CPAP at any pressure level at the time of study * The infant must be receiving 22-40% at the time of the study Exclusion Criteria: * Oxygen requirements greater than 40% at time of enrollment * currently receiving invasive ventilation or not requiring ventilatory support * Major congenital anomalies of the heart and/or lungs
Interventions
- DeviceEffective oxygen delivery and lung expansion measurement
This intervention arm will involve any infant who is already on nCPAP. It will involve placing a catheter in the infant's oropharynx and wrapping soft EIT bands around the infants chest to measure effective oxygen delivery and lung expansion, respectively.
Locations (2)
- University of Arkansas for Medical SciencesLittle Rock, Arkansas
- University of Arkansas for Medical SciencesLittle Rock, Arkansas