Advanced Robotic Techniques and Rapid Onsite Evaluation for Minimally Invasive Diagnosis and Next-Generation Sequencing: the ARTEMIS Trial.
Vanderbilt University Medical Center
Summary
ARTEMIS is a multicenter randomized controlled trial. The goal is to understand whether rapid onsite evaluation during robotic assisted bronchoscopy improves the diagnostic performance of the procedure or not.
Description
Pulmonary nodules are an incredibly common finding, with millions incidentally detected in the US every year. Biopsy is often needed for diagnosis. Robotic assisted bronchoscopy (RAB) with integrated cone beam computed tomography (CBCT) has achieved diagnostic yields exceeding 80% in some studies, significantly higher than traditional methods without advanced imaging, due to the added ability to correct alignment of the bronchoscopy catheter with the target lesion in real-time. Given this, the added value of rapid on-site cytologic evaluation (ROSE) with modern bronchoscopy is an area of debat…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * ≥ 18 years of age at time of bronchoscopy * Undergoing robotic assisted bronchoscopy to biopsy a pulmonary lesion Exclusion Criteria: * Declines to participate or inability to provide informed consent. * Clinician determination that the use of ROSE is required or contraindicated for the optimal care of an individual patient * Patient enrolled in another trial that requires ROSE for PPL biopsy * Patient previously consented for this trial * Pregnant or incarcerated patients