Ohio State University Comprehensive Cancer Center
This clinical trial aims to evaluate user sensory experiences and smoking behavior when using IQOS heated tobacco products (HTPs) among adults who smoke cigarettes.
PRIMARY OBJECTIVES: I. Assess the abuse liability (appeal and sensory effects) of IQOS. II. Examine the puffing topography of IQOS. SECONDARY OBJECTIVES: I. Evaluate the impact of flavor on the sensory effects, appeal, and puffing topography of IQOS. II. Evaluate the effect of perceived harm on IQOS use behavior. EXPLORATORY OBJECTIVE: I. Examine acute changes to pulmonary health associated with IQOS use. OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants use IQOS HeatSticks (flavor matched to their usual cigarette) as much as desired (ad lib) over 60 minutes duri…
Inclusion Criteria: * Adults 21-65 years * Adults who smoke (defined as ≥ 5 days weekly use of either menthol or non-menthol cigarettes over the past 3 months) * Willing to provide informed consent and abstain from using nicotine products 12 hours before each visit * Willing to bring UBC to each study visit * Read, write and speak English Exclusion Criteria: * Current use of other non-combustible nicotine products (e.g., electronic \[e\]-cigarettes, HTPs; \[defined as ≥ 5 days weekly use in the past 30 days\]) * Planning to quit nicotine use and/or use of any smoking cessation medication in…
Use IQOS HeatSticks (flavor matched to the participant's usual cigarette)
Smoke UBC
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