Precision Prevention: Environmental Exposure Assessment in High-Risk and Early-Onset Breast Cancer Care
City of Hope Medical Center
Summary
This study evaluates patient and provider attitudes about environmental exposure risk assessments into clinical care for female patients at average or high risk for breast cancer and/or diagnosed with early onset breast cancer.
Description
PRIMARY OBJECTIVES: I. To assess patient interest and emotional responses toward EERA and return of results. II. To assess provider attitudes toward EERA integration into clinical workflows. OUTLINE: This is an observational study. Participants are assigned to 1 of 3 aims. AIM I: Average and high risk breast cancer participants and early onset breast cancer patients complete a survey over 15-25 minutes and may attend an interview over 30-45 minutes. Participants' and patients' medical records are reviewed. AIM II: COH providers complete a survey over 15-25 minutes and may attend an interv…
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * AIM 1 INCLUSION CRITERIA: * ONE of the following: * Either average risk of developing breast cancer (defined by woman with no Tyrer-Cuzick model ≥ 20%, no mention of Tyrer-Cuzick model, and no Pathogenic/Likely Pathogenic \[P/LP\] in breast cancer related genes) OR high risk of developing breast cancer (defined by ≥ 20% chance of developing breast cancer across lifetime measured by Tyrer-Cuzick model or gene mutation carrier, P/LP carrier in breast cancer related genes including BRCA1, BRCA2, BARD1, ATM, CHEK2, CDH1, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53)…
Interventions
- OtherNon-Interventional Study
Non-interventional study
Location
- City of Hope Medical CenterDuarte, California