Exercise Intervention in Primary Antibody Deficiency Disorders: A 12-week Feasibility Study
Yale University
Summary
The purpose of this study is to assess if a 12-week exercise program is safe, practical, and acceptable for adults with primary antibody deficiencies. It also looks at whether the program can improve the quality of life and help the immune system work better.
Description
Study activities will include: Completion of health questionnaires Participation in a 12-week exercise program using a mobile application Having your exercise activity tracked through the mobile application Reporting any symptoms or infections that develop Providing blood samples for immune-related testing at your patient visits. Completion of assessments at the beginning and end of study
Eligibility
- Age range
- 18–65 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Diagnosed with one of the following primary antibody deficiencies: IgG subclass deficiency, selective IgA deficiency, selective IgM deficiency, or specific antibody deficiency * Receiving care in the Section of Rheumatology, Allergy \& Immunology * Able and willing to participate in a moderate-intensity exercise program. Patients will be screened using the American College of Sports Medicine (ACSM) Pre- participation Screening Guidelines. This algorithm assesses patients for cardiovascular, renal, and metabolic disease. Those patients determined to not require further me…
Interventions
- BehavioralApp-based exercise intervention
12 week structured moderate-intensity exercise intervention delivered via a mobile application
Locations (2)
- Bridgeport HospitalMilford, Connecticut
- Yale New Haven HealthNorth Haven, Connecticut