Myo-EXERTBC: A Pilot Study Assessing Myokines During an EXErcise Regimen After Treatment for Breast Cancer
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Summary
In this pilot study, the investigators will assess the changes in myokine production based on several different exercise regimens.
Eligibility
- Age range
- 20–89 years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: 1. Age 20-89 years 2. Women prescribed exercise as a SOC 3. Women with a biopsy proven diagnosis of ductal carcinoma in situ (DCIS) or invasive carcinoma of the breast 4. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed. 5. Women with \> 3 months of resistance training experience under expert guidance at the Allegheny Health Network Exercise…
Interventions
- BehavioralConditioning Resistance Training
Participants in this group will perform a conditioning regimen from the EXERT-BCHC protocol, specifically described as "double training".
- BehavioralStrength Resistance Training
Participants in this group will perform a strength regimen from the EXERT-BCHC protocol, specifically described as "8x8".
- BehavioralHypertrophy Resistance Training
Participants in this group will perform a hypertrophy regimen from the EXERT-BCHC protocol, specifically described as the "control arm".
Location
- AHN Allegheny General HospitalPittsburgh, Pennsylvania