Nemolizumab for the Treatment of Lichen Sclerosus
University of Texas Southwestern Medical Center
Summary
Patients ≥ 18 years of age with Lichen sclerosis (LS)
Eligibility
- Age range
- 18+ years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: * Ability to comprehend and willingness to sign a written * Females only ≥18 years of age at time of screening * Documentation of biopsy-proven anogenital LS. * Baseline itch NRS score ≥ 6 in anogenital area. * Prior use of topical corticosteroid. * Participants who agree to discontinue all agents used by the participant to treat LS from the screening visit through the final safety follow-up visit, aside from rescue therapy as specified in "Concomitant therapy" in the protocol Exclusion Criteria: * Participants who do not have LS involving anogenital area. * Need for rec…
Interventions
- BiologicalNemolizumab 30 mg
Participants will be treated with subcutaneous (SC) nemolizumab injections at doses determined by patient weight.
Location
- University of Texas Southwestern Medical CenterDallas, Texas