Evaluation of Oil Pulling Mouthwash for Reduction of Dental Plaque, Gingivitis, and Selective Reduction of Bacteria
The University of Texas Health Science Center at San Antonio
Summary
The goal of this study is to scientifically evaluate the efficacy of this oil pulling oral rinse in reducing dental plaque, gingival inflammation, gingival bleeding, and selectively reducing caries- and periodontal disease-associated bacteria compared to a marketed mouthwash and a placebo oral rinse
Description
A total of 120 subjects who met all necessary requirements for selection as subjects will be stratified into three balanced groups (40 per group) according to age, gender, and their mean baseline gingivitis index measured using the Modified Gingival Index (MGI). The three groups will be randomly assigned to use one of three test mouthwashes: GuruNanda Oil Pulling oral rinse (test), Competitor's mouthwash (positive), Water-based oral rinse (placebo). Subjects will be instructed to use their assigned mouthwash as an adjunct oral hygiene product for the 8-week treatment duration. All subjects wil…
Eligibility
- Age range
- 18–70 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Adult subjects aged 18-70, that are in good health. 2. Subject must have: 1. Baseline gingival inflammation (MGI) score of at least 1.80. 2. Baseline gingival bleeding (GBI) score of ≥ 1 on at least 20 sites. 3. An overnight (12 to 18 hour abstention from any oral hygiene) dental plaque (mean) score greater than 0.6 according to the RMNPI Index. 4. Have a minimum of 20 'scorable' teeth (excluding 3rd molars). 5. The subjects should understand the information provided about the investigative nature of the treatment, possible benefits and side effects. Subjects wil…
Interventions
- Dietary SupplementGuruNanda natural Oil Pulling oral rinse
test product
- Dietary SupplementTheraBreath Plaque Control Oral Rinse
negative control
- Dietary SupplementGuruNanda water-based non-whitening mouthwash
negative control
Location
- Clinical Research Facility of the Center for Oral Health and Research, UTHSASan Antonio, Texas