Peanut Butter Glycemic Control, Cognition and Cardiovascular Health
Penn State University
Summary
The purpose of this study is to look at the effect of consuming peanut butter at breakfast on blood sugar control, cognitive function, and heart disease risk factors in middle-aged adults with prediabetes.
Description
This is a 2-period, randomized, crossover study. In random sequence order participants will undergo each of the following conditions for 12 weeks with a ≥ 8-week washout between the two periods: 1) provision of 43 g/day (1.5 oz/day) of peanut butter with instructions to consume it as part of breakfast (or the first meal of the day); 2) instructions to continue usual intake with matched study contact and resource provision. Testing will be conducted at the beginning and end of each period.
Eligibility
- Age range
- 40–65 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age 40-65 years * BMI 25 to 40 kg/m2 * HbA1c 5.7-6.4% * Low habitual intake of peanut butter (\<0.5 Tablespoons/day on average) * Have a smartphone device or be willing to use one provided by the study Exclusion Criteria: * Hemoglobin \<13.2 g/dL for men or \< 11.7 g/dL for women at screening * Fasting triglycerides \>350 mg/dL at screening * LDL-cholesterol ≥190 mg/dL assessed by the Martin-Hopkins equation at screening * ≥10% change in body weight within the 6 months prior to enrollment * Blood pressure \>140/90 mmHg at screening * Diagnosed type 1 or type 2 diabetes…
Interventions
- OtherPeanut butter
Intake of 43 g/day of peanut butter as part of breakfast (or the first meal of the day)
- OtherUsual diet
Continue intake of usual diet.
Location
- The Pennsylvania State UniversityUniversity Park, Pennsylvania