A Prospective Randomized Split-Site Study of Donor-Site Pain and Appearance Following Pelashield TM Versus Xeroform
Wake Forest University Health Sciences
Summary
The purpose of this research study is to compare the effects (good or bad) of a new skin graft dressing (PelashieldTM) compared to the one traditionally used (Xereform).
Description
A novel dressing (Pelashield) has been developed that provides wound coverage, incorporates silver for antimicrobial activity, and contains lidocaine for local analgesia. This dressing offers the potential for improved pain control, particularly for larger donor sites, and may facilitate outpatient management. However, because the dressing includes an absorbable film, there is potential for increased irritation or altered wound healing. To rigorously evaluate this product, this prospective randomized study is being done to assess both pain control and donor-site appearance outcomes. The patien…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Undergoing split-thickness skin graft harvest, with a donor site sufficiently large to allow division into two comparable halves for randomized dressing application. * Donor site located in an area amenable to standardized photography and serial appearance assessment. * Ability to provide informed consent. * Willingness and ability to participate in scheduled follow-up visits for donor-site assessment, including standardized photography. * Donor-site management expected to follow the standardized study dressing protocol for the duration of the early healing period. Excl…
Interventions
- DevicePelashield
Pelashield dressing will be applied to half of the skin graft donor site
- DeviceXeroform
Xeroform dressing will be applied to have of the skin graft donor site
Location
- Atrium Health Wake Forest BaptistWinston-Salem, North Carolina