Povidone Iodine to Prevent Early Childhood Caries
Jeffrey A. Banas
Summary
The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to answer are: 1. How will home use of Povidone Iodine, as an adjunct treatment to standard dental care, reduce the incidence of tooth decay? 2. How will home use of Povidone Iodine reduce the mouth germs responsible for tooth decay? 3. If Povidone Iodine use is accompanied by probiotic use, will its effectiveness be even better than Povidone Iodine alone? Participants will: 1. Provide a plaque sample at the beginning of the study. 2. Swab their children's teeth once a week for one month and then monthly thereafter. Some participants may be asked to use probiotic drops nightly after brushing their teeth. 3. Keep a record of compliance. 4. Return every 6 months for a dental exam and to provide a plaque sample. Keep a diary of their symptoms and the number of times they use a rescue inhaler
Description
Dental 'caries' is the term used to describe dental decay or 'cavities'. Dental caries can occur at any age but lesions prior to a child's 6th birthday qualify as 'early childhood caries' (ECC) and possibly as 'severe' early childhood caries (SECC) if the onset and severity meet definitions put forth by the American Academy of Pediatric Dentistry. ECC and SECC can have several unfortunate downstream consequences: pain, infection, nutritional deficiencies, poorer concentration in school, and social/cosmetic/financial concerns. Recent epidemiologic trends in ECC/SECC, reported by Kotha et al. (2…
Eligibility
- Age range
- 1–3 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria * 1 to 3 years of age * No plans to relocate in the next 12 months Exclusion Criteria * Thyroid condition * Antibiotic usage in the prior 3 months
Interventions
- DrugPovidone Iodine 5% Soln,Top,Kit
Home use of Povidone Iodine administered by swabbing teeth; weekly for the 1st month, monthly thereafter.
- Dietary SupplementProbiotics
Home use of Povidone Iodine coupled with daily use of a probiotic.
- DrugPlacebo
Placebo for the Povidone Iodine
Location
- University of Iowa College of DentistryIowa City, Iowa