Dietary Supplementation With EVOO Phenolics Prevents MCI Progression to Alzheimer's Disease

Summary

The goal of this clinical trial is to determine whether the extra-virgin olive oil (EVOO) phenolic dietary supplement can improve memory function and modulate biomarkers among individuals with mild cognitive impairment (MCI). The main questions it aims to answer are: * Does dietary supplementation with EVOO phenolics improve cognitive function? * What would be the effect of the EVOO dietary supplement on other MCI-related biomarkers, including vascular function and biological pathways? Researchers will compare the EVOO dietary supplements with a placebo (a look-alike substance that contains no EVOO phenolics) Participants will: * Take EVOO dietary supplements or a placebo daily for 6 months * Visit the study site during the 6-month study for screening and testing.

Eligibility

Age range

50–70 years

Sex

All

Healthy volunteers

No

Interventions

• Dietary Supplement
  EVOO-phenolics dietary supplement

  EVOO phenolic dietary supplement which is standardized to contain10 mg of EVOO total phenolics

• Dietary Supplement
  Placebo

  Placebo

Location