The Relationship Between Neurostimulation Intensity and Pupillary Dilation Reflex (PRD) in Healthy Volunteers

Children's National Research Institute

Summary

This a single site, observational study that will examine how the pupil responds to neurostimulation under different conditions in healthy adults. The objective is to measure pupillary dilation reflex (PRD) in response to increasing neurostimulation intensities using the AlgometRx device.

Eligibility

Age range: 18–60 years
Sex: All
Healthy volunteers: Yes

Detailed criteria

Inclusion Criteria: * Age 18-60 years. * In good general health (self-reported). * Able and willing to provide written informed consent. Exclusion Criteria: * Eye pathology that prevents accurate pupillometry. * Pregnancy (Self-Report) * Diagnosis of autoimmune disorders. * Diagnosis of any neuropathic disorder * Inability to complete questionnaires.

Interventions

Other
No intervention (observational study)
No intervention

Location

Children's National Hospital
Washington D.C., District of Columbia
jfinkel@childrensnational.org 202-476-4867